February 23, 1998

GENERAL SURGICAL INNOVATIONS AND ETHICON ENDO-SURGERY, INC. REVISE DISTRIBUTION AGREEMENT

Companies Sign Non-Exclusive Agreement For Hernia and Urinary Stress Incontinence Markets

Cupertino, CA, February 23, 1998 ­ General Surgical Innovations, Inc. (GSI) (Nasdaq: GSII) announced today that it signed a non-exclusive distribution agreement with Ethicon Endo-Surgery, Inc. (EES), a Johnson & Johnson company, granting them worldwide rights to distribute GSI’s SPACEMAKER® balloon dissector products in the laparoscopic hernia repair and urinary stress incontinence (USI) markets.

The agreement supersedes the December 1996 contract which granted EES exclusive worldwide sales and marketing rights to distribute GSI’s SPACEMAKER® balloon dissector products in the laparoscopic hernia repair and USI markets.

“This agreement will allow GSI to expand our domestic and international distribution network, enhancing our ability to increase market share in the hernia repair and USI markets,” stated Gregory D. Casciaro, President and Chief Operating Officer of GSI. “Ethicon is a strong partner and we look forward to continuing our relationship with them under this new agreement. We believe that the hernia repair and USI markets represent a key opportunity for GSI’s proprietary technology and our Technology Alliance Group will continue to focus on further growing our distribution network in these areas.”

GSI’s patented SPACEMAKER tissue dissection systems, based on the company’s patented balloon technology, more rapidly and gently create surgical working spaces by separating natural tissue planes without resorting to blunt dissection used in conventional open surgery or minimally invasive surgery conducted outside of a natural body cavity. In procedures using SPACEMAKER dissectors, a surgeon creates a small incision through which the balloon is inserted and placed between naturally occurring tissue layers such as muscle, fat and skin. Subsequently, the balloon is filled to a specific volume with air or saline, causing the desired dissection of the tissue planes. The balloon is then removed and the dissected space can be insufflated to open the surgical operating space created by the use of the SPACEMAKER system.

Headquartered in Cupertino, California, General Surgical Innovations, Inc. develops, manufactures and sells tissue dissection systems based on the company’s patented balloon technology for minimally invasive surgical procedures. The company’s products are specifically designed for endoscopic and laparoscopic techniques for use in general, vascular, thoracoscopic, orthopedic, cosmetic and reconstructive surgeries to create an operating space at the surgical site, which the company believes lessens tissue damage and improves patient recovery time. The company has developed a broad range of balloon shapes and sizes to be used for various surgical techniques, procedures and market segments. GSI distributes its products worldwide through a network of distribution partners and a direct sales force. For additional information, please visit the company’s World Wide Web site at www.gsii.com.

Except for the historical information contained herein, the matters discussed in this press release are forward-looking statements, the accuracy of which is necessarily subject to risks and uncertainties. Future market development and demand for the company’s products, among other matters discussed in this release, may differ significantly from the discussion of such matters in the forward-looking statements. Such differences may be based upon factors within General Surgical Innovations’ control, such as strategic planning decisions by management and reallocation of internal resources, or on factors outside of General Surgical Innovations’ control, such as scientific advances by third parties, introduction of competitive products and delays by regulatory authorities, as well as those factors set forth under the heading “Factors Affecting Future Results” in General Surgical Innovations’ Annual Report on Form 10K for the year ended June 30, 1997, Form 10Q for the quarters ended September 30, 1997 and December 31, 1997 and other company filings with the Securities and Exchange Commission.

For more information on General Surgical Innovations. via fax at no cost,
dial 800-PRO-INFO (908-544-2850 outside the U.S.), ticker symbol: GSII.

Home | Corporate Profile | Investor Information | Career Opportunities | Trade Shows | Contact Us | News
Cardiac/Vascular Patient | Cardiac/Vascular Physician | General/URO/GYN/Plastics Patient | General/URO/GYN/Plastics Physician
Copyright © 1999 General Surgical Innovations